Industry Project Research Support Officer - APC Microbiome Ireland
12 Months, Specific Purpose, Full-Time Post
Position Summary
We are currently recruiting a Research Support Officer to oversee a number of industry-funded research projects in the Microbiota-Brain-Gut Axis Theme (covering topics of Neuroscience, Physiology, Biochemistry, Microbiology, and Systems Biology) with APC Microbiome Ireland. The successful candidate will be part of a team led by Professor John Cryan and Professor Gerard Clarke in APC Microbiome Ireland, which addresses the communication between the brain and the gut, and how it can be influenced by the gastrointestinal microbiota (see Cryan et al., Physiol Rev 2019; Long-Smith et al., Annu Rev Pharmacol Toxicol 2020).
We aim to assess predicted in silico properties of gut microbes, with in vitro, ex-vivo and in-vivo activities in immune, stress, neuroendocrine and neurotransmitter systems of relevance to gut-brain axis signalling pathways. We also use cell-based assays and investigate the role of candidate microbial strains in gut-brain interactions, physiology and behaviour in animal models. We will further assess changes in immune, stress, neuroendocrine and neurotransmitter systems.
The program is highly interdisciplinary, utilizing in vitro screening models, behaviour, molecular and cellular biology, biochemistry, pharmacology, and brain circuit determination coupled with metabolomics & microbiome analysis. The successful candidate will be expected to make an outstanding contribution to the preclinical, clinical and translational arms of the laboratory and to lead the successful delivery and objectives of a variety of research projects.
The candidate should have excellent communication skills, a good command of the English language and be highly motivated to work in a multidisciplinary team. A proven track record of publication in peer reviewed journals is also expected.
Required Research Qualifications and Experience
The ideal candidate(s) should have experience with a combination of in silico bioinformatics, in vitro cell-based assays, ex-vivo tissue assays and in-vivo behavioural assays including HPLC, Gut physiology and function, Immune assays, ELISA, PCR and molecular analyses. Previous experience of gut-brain axis research is desirable, and the successful candidate will be expected to support animal behavioural studies and clinical studies. They will be self-motivated with ability to conduct independent research to a very high level. It is expected that the successful candidate will have a PhD and a strong publication record in a relevant scientific discipline (eg. Neuroscience, Physiology, Biochemistry, Microbiology, Systems Biology,) and should have experience of applying these skills and experience to the study of gut-brain axis interactions. They will be self-motivated with ability to guide and conduct independent research to a very high level.
Research Support Experience:
• Evidence of project management skills.
• Familiarity with Agresso online ordering system or equivalent.
• Evidence of working in multidisciplinary teams.
• Evidence of budget management skills.
• Experience with grant writing and report writing.
UCC is an accredited research organisation and as such can form hosting agreements with third country nationals (and non-EEA nationals) for the purpose of conducting research in the University.
Project Title: Microbiota-Gut-Brain Axis - Industry Project Research Support Officer
Post Duration: 12 Months